Alyssa Milano was born on December 19, 1972 to Lin Milano (Fashion Designer) and Thomas M. Milano (Music Editor). She has a younger brother Cory who has acted in some of Alyssa's movies. One of her first acting breaks was in the hit TV show "Who's the Boss?" with Tony Danza. She has acted along actors such as Arnold Schwarzenegger, Johnathan Silverman of TV's "The Single Guy", John Candy, Will Smith, Sean Astin, and Christian Slater.
Alyssa produced a teen workout video in 1988 called Teen Steam. She starred in several adult targeted films such as Casualties of Love, Embrace of the Vampire, Deadly Sins and Confessions of a Sorority Girl. She gained success in TV as Jennifer Mancini on Melrose Place (1997-1998). In 2007, Alyssa Milano has appeared in commercials of Veet which is a hair removal product. The same year, she launched her signature "Touch" line of team apparel for female baseball fans. It also became available in 2009 through a boutique store located in Citi Field, the home of the New York Mets.
On stage, Alyssa Milano starred in Tender Offer, a one-act play written by Wendy Wasserstein, All Night Long by American playwright John O'Keefe and the first American musical adaptation of Jane Eyre. She also appeared in the Josie music video by Blink-182 and sang in the choir on the song "Voices That Care."
In 2007, Milano appeared in an advertisement in support of PETA in a dress made entirely of vegetables, advocating vegetarianism.
Milano has eight tattoos on her body, including one on each wrist and ankle, shoulder, neck, hip, and lower back. Outside of acting, her hobbies include photography and humanitarian work.